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Sedative effect of intranasal spray with midazolam in sedation pediatric dental patients

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Abstract


According to Fukuta¢¥s behavior rating scale, behavior were checked for evaluation of the clinical sedative effect.
The obtained results were as follows
1. Behavior score of intranasal spray with midazolam was inferior to intranasal drop with mida; olam(p<0.01).
2. Pulse rate was not affected significantly by adiministration route of drug, however there was a significant change as a function of dental procedure (F -22.6, P<0.001).
3. The peripheral oxygen saturation was not influenced significantly by either adiministration route of drug or dental procedure.
4. There were no clinical signs of significant cyanosis and respiratory depression.
Clinically intranasal spray with midazolam were safe and effective sedation in young children undergoing pediatric dental procedures.

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